Woolly Mammoth to be cloned

Within five years, a woolly mammoth will likely be cloned, according to scientists who have just recovered well-preserved bone marrow in a mammoth thigh bone.

Japan's Kyodo News first reported the find. Russian scientist Semyon Grigoriev, acting director of the Sakha Republic's mammoth museum, and colleagues are now analyzing the marrow, which they extracted from the mammoth's femur, found in Siberian permafrost soil. Grigoriev and his team, along with colleagues from Japan's Kinki University, have announced that they will launch a joint research project next year aimed at re-creating the enormous mammal, which went extinct around 10,000 years ago.

 Mammoths used to be a common sight on the landscape of North America and Eurasia. Many of our distant ancestors probably had regular face-to-face encounters with the elephant-like giants.

The key to cloning the woolly mammoth is to replace the nuclei of egg cells from an elephant with those extracted from the mammoth's bone marrow cells. Doing this, according to the researchers, can result in embryos with mammoth DNA. What's been missing is woolly mammoth nuclei with undamaged genes. Scientists have been on a Holy Grail-type search for such pristine nuclei since the late 1990s. Now it sounds like the missing genes may have been found.

In an odd twist, global warming may be responsible for the breakthrough. Warmer temperatures tied to global warming have thawed ground in eastern Russia that is almost always permanently frozen. As a result, researchers have found a fair number of well-preserved frozen mammoths there, including the one that yielded the bone marrow.